Publications
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2025
45. Lymph-node inspired hydrogels enhance CAR expression and proliferation of CAR T cells
Castellote-Borrell M., Domingo M., Merlina F., Lu H., Colell S., Bachiller M., Juan M., Guedan S., Faraudo J., Guasch J. ACS Appl. Mater. Interfaces 2025, accepted.
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2024
44. 3D Printing as a Strategy to Scale-Up Biohybrid Hydrogels for T Cell Manufacture
Pérez Del Río E., Rey-Vinolas S., Santos F., Castellote-Borrell M., Merlina F., Veciana J., Ratera I., Mateos-Timoneda M.A., Engel E., Guasch J. ACS Appl. Mater. Interfaces 2024, 16, 50139.
43. A Novel 3D Hydrogel Culture System Mimics the Lymph Node and Induces CLL Survival and Proliferation
Playà-Albinyana H., Garcia-Perez A., Otin S., Castellote-Borrell M., Campo E., Perez Galan P., Guasch J., Colomer D. Blood 2024, 144, 3234.
42. Patient-Derived Follicular Lymphoma Tumoroids: A Tool to Recapitulate Biological Features of Low and High-Grade Lymphoma
Gimenez R., Serrat N., Castellote-Borrell M., Jiménez-Martínez V., Pérez del Río E., Bachiller M., Araujo-Ayala F., Pérez R.F., Martínez-Farran A., Robles J.A., Lopez-Guillermo A., Campo E., Villanueva J., Guedan S., Martin-Subero J.I., Guasch J., Hodson D.J., Colomer D., Pérez Galán P. Blood 2024, 144, 1613.
41. Migration of human T cells can be differentially directed by electric fields depending on the extracellular microenvironment
Ende K., Santos F., Guasch J., Kemkemer R. iScience 2024, 27(5), 109746.
40. pH-Sensitive Acrylic Terpolymers for the Coating of Orally Administered Drugs Used for Colonic Release
Suárez L.M., Hoyos L., Castellote-Borrell M., Guasch J., Orozco V.H., Giraldo L.F. ACS Omega 2024, 9(1), 204.
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2023
39. 3D cell culture of CAR T cells originated from peripheral blood mononuclear cells towards cellular therapies
Pérez del Río E., Román Alonso M., Rius I., Santos F., Castellote-Borrell M., Veciana J., Ratera I., Arribas J., Guasch J. Cytotherapy 2023, 25(12), 1293.38. Biohybrid synthetic hydrogels for tumoroid culture
Castellote-Borrell M., Merlina F., Rodríguez A.R., Guasch J. Adv. Biol. 2023, 2300118.37. 2250P Exploring tumor microenvironment in lung cancer through patient-derived 3D models
Juciute N., Boada-Acosta L.A., Torres-Martínez S., Escorihuela E., Munera Maravilla E., Mosqueda-Frometa M., Castellote-Borrell M., Rodriguez A., Miranda N., Roz L., Navarro-Cerveró L., Blanco B., Guasch J., Guijarro R., Pastor-Martinez E., Calabuig Fariñas S., Camps Herrero C., Jantus Lewintre E.. Ann. Oncol. 2023, 34, S1158.36. Ratiometric Nanothermometer Based on a Radical Excimer for In Vivo Sensing
Blasi D., Gonzalez-Pato N., Rodriguez X.R., Diez-Zabala I., Srinivasan S.Y., Camarero N., Esquivias O., Roldán M., Guasch J., Laromaine A., Gorostiza P., Veciana J., Ratera I. Small 2023, 19, 2207806.35. Antibiofilm surfaces based on the immobilization of a novel recombinant antimicrobial multidomain protein using self-assembly monolayers
Kyvik A.R., Roca R., Mayolo-Deloisa K., Rodriguez X.R., Martínez-Miguel M., Martos M., Köber M., Ventosa N., Veciana J., Guasch J., Garcia-Fruitós E., Arís A.P., Ratera I. Mater. Adv. 2023, 4, 2354.34. A Novel Generation of Tailored Antimicrobial Drugs Based on Recombinant Multidomain Proteins
López-Cano A., Ferrer-Miralles N., Sánchez J., Carratalá J.V., Rodriguez X.R., Ratera I., Guasch J., Pich O.Q., Bierge P., Garcia-de-la-Maria C., Miro J.M., Garcia-Fruitós E., Arís A.P. Pharmaceutics 2023, 15(4), 1068.33. Electroactive substrates for surface-enhanced Raman spectroscopy based on overgrown gold-nanoparticle arrays by electrodeposition on indium tin oxide
González-Pato, N.; Rodriguez, X. R.; Pellizi, N.; Fasolato, C.; Guasch, J.; Postorino, P; Veciana, J.; Goñi, A. R.; Ratera, I. Mater. Adv. 2023, 4, 1378. -
2022
32. Hierarchical Quatsome-RGD Nanoarchitectonic Surfaces for Enhanced Integrin-Mediated Cell Adhesion
Martínez-Miguel, M.; Castellote-Borrell, M.; Köber, M.; Kyvik, A. R.; Tomsen-Melero, J.; Vargas-Nadal, G.; Muñoz, J.; Pulido, D.; Cristóbal-Lecina, E.; Passemard, S.; Royo, M.; Mas-Torrent, M.; Veciana, J.; Giannotti, M. I.; Guasch, J.; Ventosa, N.; Ratera, I., ACS Appl. Mater. Interfaces, 2022, 14(42), 48179.31. Enhanced human T cell expansion with inverse opal hydrogels
Santos F.; Valderas-Gutiérrez, J.; Pérez del Río E.; Castellote-Borrell, M; Rodriguez Rodriguez, X.; Veciana, J.; Ratera, I.; Guasch, J. Biomater. Sci., 2022, 10, 3730.30. Exploring the impact of the recombinant Escherichia coli strain on defensins antimicrobial activity: BL21 versus Origami strain
López-Cano A.; Martínez-Miguel, M.; Guasch, J.; Ratera, I.; Arís A.; Garcia-Fruitós E. Microb. Cell Factories, 2022, 21, 77.29. Methods for the Characterization of Protein Aggregates
Martínez-Miguel, M.; Tatkiewicz, W.; Köber, M.; Veciana, J.; Ventosa N. ; Guasch, J.; Ratera, I. Methods in Molecular Biology 2022, 2406, 479. (book chapter)28. Methods for Processing Protein Aggregates into Surfaces
Martínez-Miguel, M.; Tatkiewicz, W.; Köber, M.; Veciana, J.; Ventosa N. ; Guasch, J.; Ratera, I. Methods in Molecular Biology 2022, 2406, 517. (book chapter) -
2021
27. Polylactide, Processed by a Foaming Method Using Compressed Freon R134a, for Tissue Engineering
Aguado, M.; Saldaña, L.; Pérez del Río, E.; Guasch, J.; Parera, M.; Córdoba, A.; Seras-Franzoso, J.; Cano-Garrido, O.; Vázquez, E.; Villaverde, A.; Veciana, J.; Ratera, I.; Vilaboa, N.; Ventosa N. Polymers 2021, 13(20), 3453. -
2020
- CCL21-loaded 3D hydrogels for T cell expansion and differentiation
Pérez del Río, E.; Santos, F.; Rodriguez, X. R.; Martínez-Miguel, M.; Roca-Pinilla, R.; Arís, A.; Garcia-Fruitós, E.; Veciana, J.; Spatz, J. P.; Ratera, I.; Guasch, J. Biomaterials 2020, 120313.
- Stable anchoring of bacteria-based protein nanoparticles for surface enhanced cell guidance
Martínez-Miguel, M.; Kyvik, A. R.; M. Ernst, L.; Martínez-Moreno, A.; Cano-Garrido, O.; Garcia-Fruitós, E.; Vazquez, E.; Ventosa, N.; Guasch, J.; Veciana, J.; Villaverde, A.; Ratera, I. J. Mater. Chem. B 2020, 8 (23), 5080.
- CCL21-loaded 3D hydrogels for T cell expansion and differentiation
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2019
- High-Throughput Cell Motility Studies on Surface-Bound Protein Nanoparticles with Diverse Structural and Compositional Characteristics
Tatkiewicz, W.; Seras-Franzoso, J.; García-Fruitós, E.; Vazquez, E.; Kyvik, A. R.; Ventosa, N.; Guasch, J.; Villaverde, A.; Veciana, J.; Ratera, I. ACS Biomater. Sci. Eng. 2019, 5 (10), 5470.
- Two-dimensional self-assembly and electrical properties of the donor-acceptor tetrathiafulvalene-polychlorotriphenylmethyl radical on graphite substrates
Guasch, J.; Crivillers, N.; Souto, M.; Ratera, I.; Rovira, C.; Samorì, P.; Veciana, J. J. Appl. Phys. 2019, 125 (14), 142909.
- Cell Type-Dependent Integrin Distribution in Adhesion and Migration Responses on Protein-Coated Microgrooved Substrates
Sales, A.; Ende, K.; Diemer, J.; Kyvik, A. R.; Veciana, J.; Ratera, I.; Kemkemer, R.; Spatz, J. P.; Guasch, J. ACS Omega 2019, 4 (1), 1791.
- Functionalization of polyacrylamide for nanotrapping positively charged biomolecules
Davydova, N.; Rodriguez, X. R.; Blázquez, C.; Gómez, A.; Perevyazko, I.; Guasch, J.; Sergeev, V.; Laukhina, E.; Ratera, I.; Veciana, J. RSC Adv. 2019, 9 (27), 15402.
- High-Throughput Cell Motility Studies on Surface-Bound Protein Nanoparticles with Diverse Structural and Compositional Characteristics
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2018
- Combining Adhesive Nanostructured Surfaces and Costimulatory Signals to Increase T Cell Activation
Guasch, J.; Hoffmann, M.; Diemer, J.; Riahinezhad, H.; Neubauer, S.; Kessler, H.; Spatz, J. P. Nano Lett. 2018, 18 (9), 5899.
- Surface-Bound Gradient Deposition of Protein Nanoparticles for Cell Motility Studies
Tatkiewicz, W. I.; Seras-Franzoso, J.; Garcia-Fruitós, E.; Vazquez, E.; Kyvik, A. R.; Guasch, J.; Villaverde, A.; Veciana, J.; Ratera, I. ACS Appl. Mater. Interfaces 2018, 10 (30), 25779.
- Artificial 3D Culture Systems for T Cell Expansion
Pérez del Río, E.; Martinez Miguel, M.; Veciana, J.; Ratera, I.; Guasch, J. ACS Omega 2018, 3, 5273.
- Stimuli-Responsive Functionalization Strategies to Spatially and Temporally Control Surface Properties: Michael vs Diels–Alder Type Additions
Kyvik, A. R.; Luque-Corredera, C.; Pulido, D.; Royo, M.; Veciana, J.; Guasch, J.; Ratera, I. J. Phys. Chem. B 2018, 122 (16), 4481.
- Combining Adhesive Nanostructured Surfaces and Costimulatory Signals to Increase T Cell Activation
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2017
- Integrin-Assisted T-Cell Activation on Nanostructured Hydrogels
Guasch, J.; Muth, C. A.; Diemer, J.; Riahinezhad, H.; Spatz, J. P. Nano Lett. 2017, 17 (10), 6110.
- Integrin-Assisted T-Cell Activation on Nanostructured Hydrogels
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2016
- Synthesis of Binary Nanopatterns on Hydrogels for Initiating Cellular Responses
Guasch, J.; Diemer, J.; Riahinezhad, H.; Neubauer, S.; Kessler, H.; Spatz, J. P. Chem. Mater. 2016, 28 (6), 1806.
- Synthesis of Binary Nanopatterns on Hydrogels for Initiating Cellular Responses
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2015
- Segregation Versus Colocalization: Orthogonally Functionalized Binary Micropatterned Substrates Regulate the Molecular Distribution in Focal Adhesions
Guasch, J.; Conings, B.; Neubauer, S.; Rechenmacher, F.; Ende, K.; Rolli, C. G.; Kappel, C.; Schaufler, V.; Micoulet, A.; Kessler, H.; Boyen, H.-G.; Cavalcanti-Adam, E. A.; Spatz, J. P. Adv. Mater. 2015, 27, 3737.
- Segregation Versus Colocalization: Orthogonally Functionalized Binary Micropatterned Substrates Regulate the Molecular Distribution in Focal Adhesions
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2014
- Intramolecular electron transfer and charge delocalization in bistable donor–acceptor systems based on perchlorotriphenylmethyl radicals linked to ferrocene and tetrathiafulvalene units
Souto, M.; Morales, D. C.; Guasch, J.; Ratera, I.; Rovira, C.; Painelli, A.; Veciana, J. J. Phys. Org. Chem. 2014, 27 (6), 465.
- Intramolecular electron transfer and charge delocalization in bistable donor–acceptor systems based on perchlorotriphenylmethyl radicals linked to ferrocene and tetrathiafulvalene units
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2013
- Thermomagnetic Molecular System Based on TTF-PTM Radical: Switching the Spin and Charge Delocalization
Souto, M.; Guasch, J.; Lloveras, V.; Mayorga, P.; Navarrete, J. T. L. e.; Casado, J.; Ratera, I.; Rovira, C.; Painelli, A.; Veciana, J. J. Phys. Chem. Lett. 2013, 4, 2721.
- A Molecular Toolkit for the Functionalization of Titanium‐Based Biomaterials That Selectively Control Integrin‐Mediated Cell Adhesion
Rechenmacher, F.; Neubauer, S.; Mas-Moruno, C.; Dorfner, P. M.; Polleux, J.; Guasch, J.; Conings, B.; Boyen, H.-G.; Bochen, A.; Sobahi, T. R.; Burgkart, R.; Spatz, J. P.; Fässler, R.; Kessler, H. Chem. Eur. J. 2013, 19, 9218.
- Intra-and Intermolecular Charge Transfer in Aggregates of Tetrathiafulvalene-Triphenylmethyl Radical Derivatives in Solution
Guasch, J.; Grisanti, L.; Souto, M.; Lloveras, V.; Vidal-Gancedo, J.; Ratera, I.; Painelli, A.; Rovira, C.; Veciana, J. J. Am. Chem. Soc. 2013, 135, 6958.
- Bistability of Fc-PTM-Based Dyads: The Role of the Donor Strength
Guasch, J.; Grisanti, L.; Jung, S.; Morales, D.; D’Avino, G.; Souto, M.; Fontrodona, X.; Painelli, A.; Renz, F.; Ratera, I.; Veciana, J. Chem. Mater. 2013, 25, 808.
- The perchlorotriphenylmethyl (PTM) radical
Guasch, J.; Fontrodona, X.; Ratera, I.; Rovira, C.; Veciana, J. Acta Crystallogr. 2013, C69, 255.
- Thermomagnetic Molecular System Based on TTF-PTM Radical: Switching the Spin and Charge Delocalization
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2012
- Induced Self‐Assembly of a Tetrathiafulvalene‐Based Open‐Shell Dyad through Intramolecular Electron Transfer
Guasch, J.; Grisanti, L.; Lloveras, V.; Vidal-Gancedo, J.; Souto, M.; Morales, D. C.; Vilaseca, M.; Sissa, C.; Painelli, A.; Ratera, I.; Rovira, C.; Veciana, J. Angew. Chem. Int. Ed. 2012, 51, 11024.
- Induced Self‐Assembly of a Tetrathiafulvalene‐Based Open‐Shell Dyad through Intramolecular Electron Transfer
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2011
- Electronic and Cytotoxic Properties of 2-Amino-naphtho[2,3-b]furan-4,9-diones
Jiménez-Alonso, S.; Guasch, J.; Estévez-Braun, A.; Ratera, I.; Veciana, J.; Ravelo, A. G. J. Org. Chem. 2011, 76, 1634.
- Electronic and Cytotoxic Properties of 2-Amino-naphtho[2,3-b]furan-4,9-diones
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2009
- Essential State Models for Solvatochromism in Donor− Acceptor Molecules: The Role of the Bridge
Grisanti, L.; D’Avino, G.; Painelli, A.; Guasch, J.; Ratera, I.; Veciana, J. J. Phys. Chem. B 2009, 113 (14), 4718.
- Cooperativity from electrostatic interactions: understanding bistability in molecular crystals
D’Avino, G.; Grisanti, L.; Painelli, A.; Guasch, J.; Ratera, I.; Veciana, J. CrystEngComm 2009, 11, 2040.
- Essential State Models for Solvatochromism in Donor− Acceptor Molecules: The Role of the Bridge
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2008
- Bistability in Fc-PTM crystals: The role of intermolecular electrostatic interactions
D’Avino, G.; Grisanti, L.; Guasch, J.; Ratera, I.; Veciana, J.; Painelli, A. J. Am. Chem. Soc. 2008, 130, 12064.
- Bistability in Fc-PTM crystals: The role of intermolecular electrostatic interactions
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2006
- p-Nitrobenzyloxycarbonyl (pNZ) as an Alternative to Fmoc for the Protection of Amines in Solid-Phase Peptide Synthesis
Isidro-Llobet, A.; Guasch-Camell, J.; Álvarez, M.; Albericio, F.. In Understanding Biology Using Peptides (Proceedings of the Nineteenth American Peptide Symposium), Blondelle, S. E., Ed. Springer: 2006; 116.
- p-Nitrobenzyloxycarbonyl (pNZ) as an Alternative to Fmoc for the Protection of Amines in Solid-Phase Peptide Synthesis
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2005
- p‐Nitrobenzyloxycarbonyl (pNZ) as a Temporary Nα‐Protecting Group in Orthogonal Solid‐Phase Peptide Synthesis–Avoiding Diketopiperazine and Aspartimide Formation
Isidro-Llobet, A.; Guasch-Camell, J.; Álvarez, M.; Albericio, F. Eur. J. Org. Chem. 2005, 2005 (14), 3031.
- p‐Nitrobenzyloxycarbonyl (pNZ) as a Temporary Nα‐Protecting Group in Orthogonal Solid‐Phase Peptide Synthesis–Avoiding Diketopiperazine and Aspartimide Formation