We develop different 3D synthetic and hybrid hydrogels to imitate extracellular matrices of different healthy and diseased tissues, especially from the immune system, with the objectives to 1) elucidate cancer- and immunotherapy-related cellular mechanisms, 2) improve immune cell cultures, and 3) develop novel patient-derived organoids, to have a positive influence on cancer (immuno)therapy and related disciplines.
We develop different functional 2D nanostructured surfaces on rigid substrates and hydrogels based on the block copolymer micellar lithography technique. These functional nanostructures are used to study the influence of different biomolecules and their cross-talk on (T) cell behavior.
Institute of Materials Science of Barcelona (ICMAB-CSIC)
Til·lers, s/n, Campus de la UAB, 08193 Bellaterra, Spain
Tel. +34 93 5801853
Max Planck Institute for Medical Research
Jahnstraße 29, 69120 Heidelberg, Germany